Leading the research on HIV
The Crofoot Research Center, INC. is proud to be a leading center for the research of HIV, Hepatitis C, and Covid-19 treatments and preventatives in Houston and South Texas.
About Crofoot Research Center
The Crofoot Research Center, INC. is proud to be a leading center for the research of HIV, Hepatitis B, RSV, HPV, Hepatitis C, Covid-19 treatments and preventatives in Houston and South Texas.
Our Research Department conducts Phase I-IV studies and is comprised of Physicians, Nurse Practitioners, a Physician Assistant, a Vocational Nurse, dedicated Research Assistants, and Certified Clinical Research Professionals. Participation in clinical research allows us to offer our patients experimental treatment options that are not available elsewhere in the city, the state, and sometimes the Southeast United States.
The Crofoot Research Center, INC. is among some of the most respected clinical trial sites in Houston, TX, and excels at providing our patients as well as those from referring physicians with state-of-the-art treatment options and a highly patient-focused medical experience that respects privacy and dignity.
For information on our current Clinical Trials, including HIV research studies, please contact us or complete our fillable form.
Research & Publications
At Crofoot MD, our commitment to advancing LGBTQIA+ healthcare extends beyond patient care to pioneering research and thought leadership. Our team actively contributes to the medical community through published studies, clinical trials, and educational initiatives. By staying at the forefront of medical research, we strive to enhance treatment options, promote health equity, and ensure that our findings drive meaningful change in the lives of our patients and the broader community.
Help us make history
The Crofoot Research Center is proud to be a trusted and respected clinical trial site in Houston. We are grateful for the opportunity to contribute to medical advancements that improve the lives of individuals around the world.
Interested in learning more about our current clinical trials, including HIV research studies? Contact us today or complete the form on our website.
Current Studies Enrolling
Gilead | GS-US-563-5925 – ISLEND-1 (HIV Treatment – Comparing Weekly Dosing of Islatravir/Lenacapavir vs. Daily Dosing of Biktarvy)
A Phase 3, Randomized, Active-controlled, Double-blind Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir (B/F/TAF).
Currently Enrolling Diverse Populations Including: African American, Hispanic, Female, OR Any Race/Ethnicity who is 65 Years or Older.
Gilead | GS-US-563-5926 – ISLEND-2 (HIV Treatment – Comparing Weekly Dosing of Islatravir/Lenacapavir vs. Daily Dosing of other Standard of Care Treatments)
A Phase 3 Randomized, Active-Controlled, Open-Label Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People with HIV-1 Who are Virologically Suppressed on Standard of Care.
Currently Enrolling Diverse Populations Including: African American, Hispanic, Female, OR Any Race/Ethnicity who is 65 Years or Older.
Gilead | GS-US-685-6819 (RSV Treatment)
A Phase 2 Randomized, Placebo-controlled Study of the Safety and Efficacy of Obeldesivir to Treat Non-hospitalized Adults with Acute Respiratory Syncytial Virus (RSV) Infection.Currently Enrolling Persons with a Confirmed Positive RSV Test with AT LEAST ONE of the Following Risk Factors: 60 Years or Older, Moderate or Severe COPD, Asthma, Chronic Lung Disease, OR Chronic Cardiovascular Disease.
Pfizer | C5091017 (Covid Treatment)
An Interventional Efficacy and Safety, Phase 3, Double-Blind, 2-Arm Study to Investigate Orally Administered Ibuzatrelvir Compared With Placebo in Non-Hospitalized Symptomatic Adult and Adolescent Participants With COVID-19 Who Are at High Risk of Progressing to Severe Illness.
Gilead | GS-US-563-5925 – ISLEND-1 (HIV Treatment – Comparing Weekly Dosing of Islatravir/Lenacapavir vs. Daily Dosing of Biktarvy)
A Phase 3, Randomized, Active-controlled, Double-blind Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir (B/F/TAF)
Currently Enrolling Diverse Populations Including: African American, Hispanic, Female, OR Any Race/Ethnicity who is 65 Years or Older
Gilead | GS-US-563-5926 – ISLEND-2 (HIV Treatment – Comparing Weekly Dosing of Islatravir/Lenacapavir vs. Daily Dosing of other Standard of Care Treatments)
A Phase 3 Randomized, Active-Controlled, Open-Label Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People with HIV-1 Who are Virologically Suppressed on Standard of Care
Gilead | GS-US-685-6819 (RSV Treatment)
A Phase 2 Randomized, Placebo-controlled Study of the Safety and Efficacy of Obeldesivir to Treat Non-hospitalized Adults with Acute Respiratory Syncytial Virus (RSV) Infection
Currently Enrolling Persons with a Confirmed Positive RSV Test with AT LEAST ONE of the Following Risk Factors: 60 Years or Older, Moderate or Severe COPD, Asthma, Chronic Lung Disease, OR Chronic Cardiovascular Disease.
Pfizer | C5091017 (Covid Treatment)
An Interventional Efficacy and Safety, Phase 3, Double-Blind, 2-Arm Study to Investigate Orally Administered Ibuzatrelvir Compared With Placebo in Non-Hospitalized Symptomatic Adult and Adolescent Participants With COVID-19 Who Are at High Risk of Progressing to Severe Illness
Currently Enrolling:
- 18 to 49 years of age with at least two risk factors (listed below) where one MUST BE moderate immunocompromise.
- 50 to 64 years of age with at least two risk factors (listed below).
- 65 to 74 years of age with at least one risk factors (listed below).
- 75 years or older, with no requirements related to risk factors.
Risk Factors Include:
- BMI ≥30 kg/m2;
- Current smoker (cigarette smoking within the past 30 days) and history of at least 100 lifetime cigarettes;
- Chronic lung disease (ie, bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease, interstitial lung disease, history of pulmonary embolism, pulmonary hypertension);
- Asthma, requiring daily prescribed therapy;
- Cardiovascular disease, defined as history of any of the following: coronary artery disease, cardiomyopathies, myocardial infarction, stroke, transient ischemic attack, heart failure, angina with prescribed nitroglycerin, coronary artery bypass graft, percutaneous coronary intervention, carotid endarterectomy, and aortic bypass;
- Type 1 or Type 2 diabetes mellitus;
- Mild to moderate renal impairment provided participant doesn't meet Exclusion Criterion 2;
- Neurodevelopmental disorders (eg, cerebral palsy, Down's syndrome) or other conditions that confer medical complexity (eg, genetic or metabolic syndromes and severe congenital anomalies), as long as the cognitive function allows consenting and completion of study procedures (eg, diaries);
- Sickle cell disease;
- Moderate immunosuppression: Such as HIV infection with current CD4 count ≤350 cells/µL, T cell (cellular) immunodeficiencies, B cell (cellular) immunodeficiencies, Wiskott-Aldrich syndrome, Ataxia telangiectasia, Di George syndrome, Chronic granulomatous disease, Chronic granulomatous disease.
Current Studies
GlaskoSmithKline (GSK) | 209639 – EMBRACE (HIV Treatment – 4 Month Infusion)
A Phase 2b Multicentre, Randomized, Open-Label Study Comparing the Efficacy, Safety, PK, and Tolerability of VH3810109, Administered Subcutaneously as Either an Injection or Infusion with rHuPH20, in Combination with CAB LA to DTG/3TC in Virologically Suppressed Adults Living with HIV.
Gilead | GS-US-528-9023 – PURPOSE-2 (HIV Prevention – 6 Month Injection)
A Phase 3, Double-Blind, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Subcutaneous Twice Yearly Long-Acting Lenacapavir for HIV Pre-Exposure Prophylaxis in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People ≥16 Years of Age who Have Sex with Male Partners and are at Risk for HIV Infection.
Gilead | GS-US-536-5939 (HIV Treatment – 6 Month Infusion)
A Phase 2 Randomized, Open-label Study to Evaluate the Safety and Efficacy of Broadly Neutralizing Antibodies (bNAbs) GS-5423 and GS-2872 in Combination With the Capsid Inhibitor Lenacapavir as Long-Acting Treatment Dosed Every 6 Months in Virologically Suppressed Adults With HIV-1 Infection.
Gilead | GS-US-563-6041 (HIV Treatment)
A Phase 2 Randomized, Open Label, Active Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of Lenacapavir and Islatravir in Virally Suppressed People with HIV.
Gilead | GS-US-621-6289 – ARTISTRY-1 (HIV Treatment)
An Operationally Seamless Phase 2/3 Randomized, Open-label, Multicenter, Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Stable Baseline Regimen in Virologically Suppressed People With HIV-1 on Stable Complex Treatment Regimens.
Gilead | GS-US-621-6290 – ARTISTRY-2 (HIV Treatment)
Phase 3 Double-Blind Multicenter Randomized Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Biktarvy® (Bictegravir/Emtricitabine/Tenofovir Alafenamide) in Virologically Suppressed People with HIV-1.
Gilead | GS-US-695-6509 – WONDERS-1 (HIV Treatment)
An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination with GS-4182 in Virologically Suppressed People with HIV.
Merck | MK-8591A-051 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy.
Merck | MK-8591A-052 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF).
Merck | MK-8591A-054 (HIV Treatment)
A Phase 3 Open-label Clinical Study of Doravirine/Islatravir (DOR/ISL [100 mg/0.25 mg]) Once Daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL (100 mg/0.75 mg) QD in a Phase 3 Clinical Study.
A Phase 2b Multicentre, Randomized, Open-Label Study Comparing the Efficacy, Safety, PK, and Tolerability of VH3810109, Administered Subcutaneously as Either an Injection or Infusion with rHuPH20, in Combination with CAB LA to DTG/3TC in Virologically Suppressed Adults Living with HIV.
Gilead | GS-US-528-9023 – PURPOSE-2 (HIV Prevention – 6 Month Injection)
A Phase 3, Double-Blind, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Subcutaneous Twice Yearly Long-Acting Lenacapavir for HIV Pre-Exposure Prophylaxis in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People ≥16 Years of Age who Have Sex with Male Partners and are at Risk for HIV Infection.
Gilead | GS-US-536-5939 (HIV Treatment – 6 Month Infusion)
A Phase 2 Randomized, Open-label Study to Evaluate the Safety and Efficacy of Broadly Neutralizing Antibodies (bNAbs) GS-5423 and GS-2872 in Combination With the Capsid Inhibitor Lenacapavir as Long-Acting Treatment Dosed Every 6 Months in Virologically Suppressed Adults With HIV-1 Infection.
Gilead | GS-US-563-6041 (HIV Treatment)
A Phase 2 Randomized, Open Label, Active Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of Lenacapavir and Islatravir in Virally Suppressed People with HIV.
Gilead | GS-US-621-6289 – ARTISTRY-1 (HIV Treatment)
An Operationally Seamless Phase 2/3 Randomized, Open-label, Multicenter, Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Stable Baseline Regimen in Virologically Suppressed People With HIV-1 on Stable Complex Treatment Regimens.
Gilead | GS-US-621-6290 – ARTISTRY-2 (HIV Treatment)
Phase 3 Double-Blind Multicenter Randomized Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Biktarvy® (Bictegravir/Emtricitabine/Tenofovir Alafenamide) in Virologically Suppressed People with HIV-1.
Gilead | GS-US-695-6509 – WONDERS-1 (HIV Treatment)
An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination with GS-4182 in Virologically Suppressed People with HIV.
Merck | MK-8591A-051 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy.
Merck | MK-8591A-052 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF).
Merck | MK-8591A-054 (HIV Treatment)
A Phase 3 Open-label Clinical Study of Doravirine/Islatravir (DOR/ISL [100 mg/0.25 mg]) Once Daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL (100 mg/0.75 mg) QD in a Phase 3 Clinical Study.
Phase 3 Double-Blind Multicenter Randomized Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Biktarvy® (Bictegravir/Emtricitabine/Tenofovir Alafenamide) in Virologically Suppressed People with HIV-1.
Gilead | GS-US-695-6509 – WONDERS-1 (HIV Treatment)
An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination with GS-4182 in Virologically Suppressed People with HIV.
Merck | MK-8591A-051 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy.
Merck | MK-8591A-052 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF).
Merck | MK-8591A-054 (HIV Treatment)
A Phase 3 Open-label Clinical Study of Doravirine/Islatravir (DOR/ISL [100 mg/0.25 mg]) Once Daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL (100 mg/0.75 mg) QD in a Phase 3 Clinical Study.
GlaskoSmithKline (GSK) | 209639 – EMBRACE (HIV Treatment – 4 Month Infusion)
A Phase 2b Multicentre, Randomized, Open-Label Study Comparing the Efficacy, Safety, PK, and Tolerability of VH3810109, Administered Subcutaneously as Either an Injection or Infusion with rHuPH20, in Combination with CAB LA to DTG/3TC in Virologically Suppressed Adults Living with HIV.
Gilead | GS-US-528-9023 – PURPOSE-2 (HIV Prevention – 6 Month Injection)
A Phase 3, Double-Blind, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Subcutaneous Twice Yearly Long-Acting Lenacapavir for HIV Pre-Exposure Prophylaxis in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People ≥16 Years of Age who Have Sex with Male Partners and are at Risk for HIV Infection.
Gilead | GS-US-536-5939 (HIV Treatment – 6 Month Infusion)
A Phase 2 Randomized, Open-label Study to Evaluate the Safety and Efficacy of Broadly Neutralizing Antibodies (bNAbs) GS-5423 and GS-2872 in Combination With the Capsid Inhibitor Lenacapavir as Long-Acting Treatment Dosed Every 6 Months in Virologically Suppressed Adults With HIV-1 Infection.
Gilead | GS-US-563-6041 (HIV Treatment)
A Phase 2 Randomized, Open Label, Active Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of Lenacapavir and Islatravir in Virally Suppressed People with HIV.
Gilead | GS-US-621-6289 – ARTISTRY-1 (HIV Treatment)
An Operationally Seamless Phase 2/3 Randomized, Open-label, Multicenter, Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Stable Baseline Regimen in Virologically Suppressed People With HIV-1 on Stable Complex Treatment Regimens.
Gilead | GS-US-621-6290 – ARTISTRY-2 (HIV Treatment)
Phase 3 Double-Blind Multicenter Randomized Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Biktarvy® (Bictegravir/Emtricitabine/Tenofovir Alafenamide) in Virologically Suppressed People with HIV-1.
Gilead | GS-US-695-6509 – WONDERS-1 (HIV Treatment)
An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination with GS-4182 in Virologically Suppressed People with HIV.
Merck | MK-8591A-051 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy.
Merck | MK-8591A-052 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF).
Merck | MK-8591A-054 (HIV Treatment)
A Phase 3 Open-label Clinical Study of Doravirine/Islatravir (DOR/ISL [100 mg/0.25 mg]) Once Daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL (100 mg/0.75 mg) QD in a Phase 3 Clinical Study.
GlaskoSmithKline (GSK) | 209639 – EMBRACE (HIV Treatment – 4 Month Infusion)
A Phase 2b Multicentre, Randomized, Open-Label Study Comparing the Efficacy, Safety, PK, and Tolerability of VH3810109, Administered Subcutaneously as Either an Injection or Infusion with rHuPH20, in Combination with CAB LA to DTG/3TC in Virologically Suppressed Adults Living with HIV.
Gilead | GS-US-528-9023 – PURPOSE-2 (HIV Prevention – 6 Month Injection)
A Phase 3, Double-Blind, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Subcutaneous Twice Yearly Long-Acting Lenacapavir for HIV Pre-Exposure Prophylaxis in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People ≥16 Years of Age who Have Sex with Male Partners and are at Risk for HIV Infection.
Gilead | GS-US-536-5939 (HIV Treatment – 6 Month Infusion)
A Phase 2 Randomized, Open-label Study to Evaluate the Safety and Efficacy of Broadly Neutralizing Antibodies (bNAbs) GS-5423 and GS-2872 in Combination With the Capsid Inhibitor Lenacapavir as Long-Acting Treatment Dosed Every 6 Months in Virologically Suppressed Adults With HIV-1 Infection.
Gilead | GS-US-563-6041 (HIV Treatment)
A Phase 2 Randomized, Open Label, Active Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of Lenacapavir and Islatravir in Virally Suppressed People with HIV.
Gilead | GS-US-621-6289 – ARTISTRY-1 (HIV Treatment)
An Operationally Seamless Phase 2/3 Randomized, Open-label, Multicenter, Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Stable Baseline Regimen in Virologically Suppressed People With HIV-1 on Stable Complex Treatment Regimens.
Gilead | GS-US-621-6290 – ARTISTRY-2 (HIV Treatment)
Phase 3 Double-Blind Multicenter Randomized Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Biktarvy® (Bictegravir/Emtricitabine/Tenofovir Alafenamide) in Virologically Suppressed People with HIV-1.
Gilead | GS-US-695-6509 – WONDERS-1 (HIV Treatment)
An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination with GS-4182 in Virologically Suppressed People with HIV.
Merck | MK-8591A-051 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy.
Merck | MK-8591A-052 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF).
Merck | MK-8591A-054 (HIV Treatment)
A Phase 3 Open-label Clinical Study of Doravirine/Islatravir (DOR/ISL [100 mg/0.25 mg]) Once Daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL (100 mg/0.75 mg) QD in a Phase 3 Clinical Study.
GlaskoSmithKline (GSK) | 209639 – EMBRACE (HIV Treatment – 4 Month Infusion)
A Phase 2b Multicentre, Randomized, Open-Label Study Comparing the Efficacy, Safety, PK, and Tolerability of VH3810109, Administered Subcutaneously as Either an Injection or Infusion with rHuPH20, in Combination with CAB LA to DTG/3TC in Virologically Suppressed Adults Living with HIV
Gilead | GS-US-528-9023 – PURPOSE-2 (HIV Prevention – 6 Month Injection)
A Phase 3, Double-Blind, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Subcutaneous Twice Yearly Long-Acting Lenacapavir for HIV Pre-Exposure Prophylaxis in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People ≥16 Years of Age who Have Sex with Male Partners and are at Risk for HIV Infection
Gilead | GS-US-536-5939 (HIV Treatment – 6 Month Infusion)
A Phase 2 Randomized, Open-label Study to Evaluate the Safety and Efficacy of Broadly Neutralizing Antibodies (bNAbs) GS-5423 and GS-2872 in Combination With the Capsid Inhibitor Lenacapavir as Long-Acting Treatment Dosed Every 6 Months in Virologically Suppressed Adults With HIV-1 Infection
Gilead | GS-US-563-6041 (HIV Treatment)
A Phase 2 Randomized, Open Label, Active Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of Lenacapavir and Islatravir in Virally Suppressed People with HIV
Gilead | GS-US-621-6289 – ARTISTRY-1 (HIV Treatment)
An Operationally Seamless Phase 2/3 Randomized, Open-label, Multicenter, Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Stable Baseline Regimen in Virologically Suppressed People With HIV-1 on Stable Complex Treatment Regimens
Gilead | GS-US-621-6290 – ARTISTRY-2 (HIV Treatment)
Phase 3 Double-Blind Multicenter Randomized Active-Controlled Study to Evaluate the Safety and Efficacy of Bictegravir/Lenacapavir Versus Biktarvy® (Bictegravir/Emtricitabine/Tenofovir Alafenamide) in Virologically Suppressed People with HIV-1
Gilead | GS-US-695-6509 – WONDERS-1 (HIV Treatment)
An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination with GS-4182 in Virologically Suppressed People with HIV
Merck | MK-8591A-051 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy
Merck | MK-8591A-052 (HIV Treatment)
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF)
Merck | MK-8591A-054 (HIV Treatment)
A Phase 3 Open-label Clinical Study of Doravirine/Islatravir (DOR/ISL [100 mg/0.25 mg]) Once Daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL (100 mg/0.75 mg) QD in a Phase 3 Clinical Study
